FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing 1,3-disubstituted urea derivatives of 1,3-dimethyladamantane of general formula: 
,
where n=0, 1
. The method involves reacting an isocyanate of general formula: 
, where n=0, 1; with amines selected from: 1,2-ethylenediamine, piperidine, 1-aminomethyladamantane, 2-amino-2-cyanoadamantane and 2-aminoethanol at temperature of 0-25°C, for 3-8 hours in dimethyl formamide with molar ratio isocyanate:amine:dimethyl formamide=1:1.1-7.2:65-107.
EFFECT: invention enables to obtain novel 1,3-disubstituted ureas of the disclosed structural formula with a low melting point.
6 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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|
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|
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|
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|
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|
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| METHOD OF OBTAINING 2-AMINO-2-CYANOADAMANTANE | 2013 |
|
RU2523462C1 |
| METHOD FOR PRODUCTION OF 2-AMINO-2-CYANOADAMANTANE OR DERIVATIVES THEREOF | 2006 |
|
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| METHOD OF PRODUCING 1-CHLORO-3-CYANOADAMANTANE | 2009 |
|
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|
RU2510962C2 |
