METHOD OF PRODUCING NOVEL POLYMER COMPOUND, HAVING ANTIVIRAL ACTIVITY BY COPOLYMERISATION OF 2,5-DIHYDROXYBENZOIC ACID AND GELATINE USING LACCASE ENZYME Russian patent published in 2013 - IPC C08H1/00 C07K2/00 C12P1/02 C12P21/00 A61K38/39 A61P31/22 

FIELD: chemistry.

SUBSTANCE: invention relates to chemical engineering and techniques for producing veterinary, medical and pharmaceutical preparations. The method of producing a novel antiviral substance based on 2,5-dihydroxybenzoic acid and gelatine includes oxidising 2,5-dihydroxybenzoic acid with laccase enzyme to intermediate phyenoxy radicals and semiquinones, which are then copolymerised with gelatine, and separating the obtained copolymer from low-molecular weight components by dialysis; optimum concentrations of components of the reaction mixture are as follows: 2,5-dihydroxybenzoic acid - 15-80 mM, gelatine - 1-13 mg/ml reaction mixture, laccase - 0.5-10 units of activity/ml reaction mixture.

EFFECT: obtained copolymer has antiviral activity on herpesvirus, particularly Aujeszky's disease virus.

2 tbl, 1 dwg, 3 ex