FIELD: water-soluble (co)polymers synthesis.
SUBSTANCE: invention relates to the synthesis of water-soluble (co)polymers of vinylphosphonic acid with their own antiviral activity, having a molecular weight of MM = (5-310)•103, which can be used to develop methods for combating infections caused by influenza viruses. The synthesis is carried out by the method for radical (co)polymerization initiated by 2,2'-azobis-isobutyronitrile (DAK) or 2,2'-azobis-(2-methylpropionamidino)dihydrochloride (AMP) in an inert atmosphere in an aqueous solution or an organic solvent. The (co)polymers obtained by this synthesis have the following structural formula:
,
where: m=13-100 mol.%, n=0-87 mol.%.
EFFECT: development of the synthesis of water-soluble non-toxic (co)polymers of vinylphosphonic acid with their own antiviral activity.
1 cl, 1 tbl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF PREVENTING RESPIRATORY VIRAL INFECTIONS (FLU) | 2022 |
|
RU2805806C1 |
WATER-SOLUBLE SULPHONATED POLYMERS WITH INTRINSIC ANTIVIRAL ACTIVITY AND METHOD FOR PRODUCTION THEREOF | 2023 |
|
RU2814298C1 |
USE OF LIPOPEPTIDES AS INHIBITORS OF MEMBRANE FUSION | 2022 |
|
RU2802823C1 |
COPOLYMERS OF N-VINYLAMIDES WITH SALTS OF HYDROXYCINNAMIC ACID | 2022 |
|
RU2796753C1 |
METHOD OF PREPARATION OF 4-HETARYL-3,6-DIOXO-2,3,4,5,6,7-HEXAHYDROISOTHIAZOLO[5,4-b]PYRIDINE-5-CARBONITRILES | 2023 |
|
RU2812610C1 |
SULFO-CONTAINING POLYMERS WITH ITS OWN ANTIVIRAL ACTIVITY | 2016 |
|
RU2635558C2 |
THREE-LAYER SOLID ELECTROLYTE MEMBRANE OF MEDIUM TEMPERATURE SOFC | 2023 |
|
RU2812650C1 |
METHOD FOR CATALYTIC DECOMPOSITION OF HYDROGEN PEROXIDE USING SILVER NANOWIRES | 2022 |
|
RU2815436C1 |
METHOD FOR DETERMINING AND QUANTIFYING SPECIFIC CELLULAR IMMUNITY TO SARS-CoV-2 VIRUS S-PROTEIN ANTIGENS | 2021 |
|
RU2762616C1 |
DIMETHYL 7-METHYL-2-(PYRROLIDINE-1-yl)-4-PHENYLPYRROLO[2,1-ƒ][1,2,4]TRIAZINE-5,6-DICARBOXYLATE AND DIMETHYL 7-METHYL-2-(4-R-PHENYL)-4-(4-R-PHENYL)PYRROLO[2,1-ƒ][1,2,4]TRIAZINE-5,6-DICARBOXYLATES EXHIBITING ANTIVIRAL ACTIVITY | 2021 |
|
RU2790376C1 |
Authors
Dates
2023-01-17—Published
2022-07-01—Filed