DIESTER NALMEFENE PRODRUGS Russian patent published in 2013 - IPC C07D489/08 A61K31/485 A61P25/32

Abstract RU 2495041 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to new compounds, namely nalmefene prodrugs of formula (I) wherein R¹ means C_16-20alkyloxycarbonylC_2-4alkyl, as well as to pharmaceutical compositions containing the above compounds, as well as to a method for preparing the above compounds.

EFFECT: compounds possess action of an opioid receptor antagonist and may be used for treating substance abuse disorders, wherein the above disorder represents abuse of alcohol and alcohol dependence.

8 cl, 1 tbl, 2 ex

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RU 2 495 041 C2

Authors

Gijom Mishel' Zhozef Moris Andre

Gakens Tim

Dates

2013-10-10—Published

2009-04-23—Filed