METHOD OF PREDICTING PROBABILITY OF LETHAL OUTCOME IN PATIENTS WITH SEPSIS Russian patent published in 2013 - IPC A61B5/145 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to intensive therapy and can be used in treatment of patients with sepsis. For this purpose clinical-laboratory analysis and tests are carried out and assessment of patient's state is given every five days by APACHE II scale. Simultaneously additionally reserve albumin binding capacity is determined. On the basis of said parameters prognostic index is determined by formula $$P{I}_n=\frac{A_n}{\left(A_n-A_{n+1}\right)}\times \frac{RAB{C}_n}{RAB{C}_{n+1}},$$ where A_n, A_n+1 are quantity of points by APACHE II scale on the first and fifth day of examined period of patient's state assessment. RABC _n, RABC_n+1 are reserve albumin binding capacity on the first and fifth day of respective period of patient's state assessment. If value PI _n<0 and PI _n>8, high probability of lethal outcome is predicted, and in case of 0 ≤ PI_n ≤ 8, low probability of lethal outcome is predicted.

EFFECT: method ensures more accurate prediction of lethal outcome in patients with sepsis, including patients with clinically positive dynamics due to determination of parameters, which make it possible to carry out integral estimation of intoxication manifestation, which will make it possible to correct performed therapy in due time.

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