METHOD FOR SIMULATING PROCESS OF FORMATION OF CALCULUS FROM ANALOGUE OF HUMAN SALIVA SOLUTION Russian patent published in 2016 - IPC G09B23/28 G01N33/487 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, specifically to dental methods for experimental simulation of processes in oral cavity, in particular calculus formation. For this purpose, a method is disclosed for simulating process of calculus formation of analogue of human saliva solution, based on synthesis of calculus in artificial model medium, where a model medium of said composition is prepared: NaCl - 9.00 mmol/l, K₂CO₃ - 5.00 mmol/l, (NH₄)₂HPO₄ - 5.60 mmol/l, NH₄Cl - 29.49 mmol/l, NH₄F - 0.01 mmol/l, KCl - 25.00 mmol/l, CaCl₂·H₂O - 6.90 mmol/l, MgCl₂·6H₂O - 3.00 mmol/l. Synthesis is carried out at pH=6.95±0.05 and temperature 37.0 ± 0.5 °C, after 60 days a phase is formed in form of brushite, and after 90 days from model system hydroxyapatite is formed, which is main component of human dental calculus.

EFFECT: invention makes it possible to detect a predisposition to disease and developing preventive measures to prevent calculus growth.

1 cl, 5 dwg, 2 tbl, 1 ex