FIELD: medicine.
SUBSTANCE: group of inventions relates to a filler containing a hyaluronic acid hydrogel. Filler for soft tissues contains a hyaluronic acid hydrogel including hyaluronic acid, a salt of hyaluronic acid, or crosslinked hyaluronic acid, wherein the ratio of lifting capacity per unit content (wt./wt.%) of hyaluronic acid contained in the filler to the degree of modification (mol.%) is from 60 to 180 ((Pa*N/ (wt./wt.)%/ mol.%); wherein the filler has all properties of high cohesive capacity of a one-phase filler with hyaluronic acid and high elasticity of a two-phase filler with hyaluronic acid. Also disclosed are a method for producing a filler, a filled syringe, a biological material for regenerating soft tissues, a method for regenerating soft tissues, and a method for reducing wrinkles.
EFFECT: group of inventions provides enhanced properties of high viscoelasticity, has the advantages of both one and two-phase fillers with a hydrogel of hyaluronic acid.
22 cl, 1 tbl, 3 ex
             
         
            
              
                | Title | Year | Author | Number | 
							
              
                | FILLER CONTAINING A HYALURONIC ACID HYDROGEL AND EXHIBITING EXCELLENT FILLING PROPERTIES | 2019 | 
										Jang, CheolKim, YeonsooLee, HyunsupLee, MyunghanKim, Ji SunJung, Hyun TaeSo, JineonLee, Chang HyunRee, Hwayoun | RU2776378C1 | 
							
              
                | FILLER WITH HYALURONIC ACID, EXHIBITING HIGH LIFTING ABILITY AND LOW INJECTION FORCE | 2019 | 
										Jang, CheolKim, Ji SunSo, JineonLee, Chang HyunLee, ChungRee, HwayounJung, Hyun Tae | RU2770541C1 | 
							
              
                | FILLER WITH HYALURONIC ACID, EXHIBITING HIGH VISCOELASTICITY AND HIGH COHESION | 2019 | 
										Jang, CheolLee, ChungKim, Ji SunJung, Hyun TaeLee, Chang HyunSo, JineonRee, Hwayoun | RU2769398C1 | 
							
              
                | HYDROGEL OF CROSS-LINKED HYALURONIC ACID CROSS-LINKED USING CROSS-LINKING AGENT AND POLYOL, AND FILLER CONTAINING THEREOF | 2022 | 
										Jung, Hyun TaeLee, ChungSo, Jineon | RU2838899C1 | 
							
              
                | METHOD FOR CROSSLIFT OF HYALURONIC ACID, METHOD FOR PREPARATION OF INJECTION HYDROGEL, HYDROGEL AND USE THEREOF | 2014 |  | RU2683286C2 | 
							
              
                | METHOD FOR PRODUCTION OF FILLER BASED ON HYALURONIC ACID, INCLUDING NEUTRALIZATION STAGE | 2017 |  | RU2790229C2 | 
							
              
                | METHOD FOR PRODUCING A FILLER BASED ON HYALURONIC ACID | 2017 |  | RU2756546C1 | 
							
              
                | METHOD FOR PRODUCING FILLER BASED ON HYALURONIC ACID, INCLUDING NEUTRALISATION STAGE | 2017 |  | RU2753514C1 | 
							
              
                | METHOD FOR PRODUCTION OF FILLER BASED ON HYALURONIC ACID, USING SPECIFIC CROSS-LINKING AGENTS | 2017 |  | RU2780323C2 | 
							
              
                | DERMAL FILLER COMPOSITION FOR SMALL WRINKLES TREATING | 2012 | 
										Ntszikan Gebriel N.Yuj SyaotszeLyu FutyanPeliual SamitManezis Nikolas Dzhej. | RU2626513C2 |