FIELD: medicine.
SUBSTANCE: what is presented is a method for prediction of a risk of disturbed fertility in males suffering obesity, involving venous blood sampling followed by the allele-specific polymerase chain reaction using a fluorescent labelled oligonucleotide probe and melting line analysis. Having found the allele A of CYP19A aromatase gene polymorphisms rs2414096 and rs749292 enables predicting the risk of disturbed fertility in males suffering obesity.
EFFECT: new prognostic indices for the estimated risk of disturbed fertility in males with obesity.
8 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTION OF EFFECTIVENESS OF AROMATASE INHIBITORS IN TREATING IDIOPATHIC STERILITY IN MALES SUFFERING OBESITY | 2012 |
|
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| METHOD FOR ASSESSING THE REPRODUCTIVE FUNCTION IN MEN WITH IDIOPATHIC INFERTILITY | 2021 |
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| PANEL FOR DETERMINING PREDISPOSITION TO DEVELOPING DISORDERS OF STEROID HORMONE METABOLISM AND ITS USE | 2024 |
|
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| METHOD OF PREDICTION OF IDIOPATHIC MALE INFERTILITY BASED ON ANALYSIS OF NUCLEOTIDE VARIANTS IN MITOCHONDRIAL CYTOCHROME B GENE | 2022 |
|
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| METHOD FOR DETERMINING RISK OF OLIGOZOOSPERMIA IN MEN WITH NORMOZOOSPERMIA | 2020 |
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| METHOD OF PREDICTION OF CLINICAL EFFECTIVENESS OF TREATMENT WITH CHORIONIC GONADOTROPIN IN MALES WITH HYPOGONADISM | 2015 |
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| METHOD FOR ASSESSING THE RISK OF PREMATURE REDUCTION OF OVARIAN RESERVE | 2022 |
|
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| METHOD FOR PREDICTING AFFECTED FERTILITY IN MEN | 2006 |
|
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| METHOD FOR FORECASTING EFFICIENCY OF LOW-INTENSITY LASER THERAPY IN SECRETORY ASTENOZOSPERMIA | 2020 |
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| METHOD OF TREATING HYPOGONADOTROPIC HYPOGONADISM, NASAL SPRAY AS METHOD FOR ADMINISTERING GONADORELIN ACETATE IN TREATING HYPOGONADOTROPIC HYPOGONADISM | 2019 |
|
RU2733465C1 |
