FIELD: molecular biology.
SUBSTANCE: what is described is a method for prediction of idiopathic male infertility involving DNA recovery and genotyping of a polymorphic variant rs25487 of the DNA repair system gene (XRCC1). According to the invention, the method employs a native ejaculate produced by way of mastication, and if the genotype GG or allele G of the polymorphic variant rs25487 is detected, a risk of developing idiopathic male infertility in the form of oligoasthenoteratospermia or asthenoteratozoospermia is predicted.
EFFECT: higher prediction accuracy.
1 cl, 1 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREDICTION OF IDIOPATHIC MALE INFERTILITY BASED ON ANALYSIS OF NUCLEOTIDE VARIANTS IN MITOCHONDRIAL CYTOCHROME B GENE | 2022 |
|
RU2800406C1 |
| METHOD FOR PREDICTING MALE INFERTILITY BASED ON SPERM DNA FRAGMENTATION ANALYSIS | 2023 |
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| METHOD FOR ASSESSING THE REPRODUCTIVE FUNCTION IN MEN WITH IDIOPATHIC INFERTILITY | 2021 |
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|
RU2789239C1 |
| METHOD FOR PREDICTION OF RISK OF DISTURBED FERTILITY IN MALES SUFFERING OBESITY | 2012 |
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| METHOD FOR PREDICTING AFFECTED FERTILITY IN MEN | 2006 |
|
RU2314530C1 |
| MALE REPRODUCTIVE FUNCTION TEST METHOD | 2023 |
|
RU2819094C1 |
| METHOD FOR DETERMINING NEED FOR ASSISTED REPRODUCTIVE TECHNOLOGIES (ART) WITH SPERM DONATION IN IDIOPATHIC MALE INFERTILITY WITH NON-OBSTRUCTIVE AZOOSPERMIA | 2023 |
|
RU2814377C1 |
| METHOD OF DETERMINING TREATMENT TACTICS FOR INFERTILITY ASSOCIATED WITH HUMAN PAPILLOMAVIRUS INFECTION IN MEN | 2023 |
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RU2806807C1 |
| METHOD OF TREATING MALE INFERTILITY WITH HIGH DNA FRAGMENTATION OF EJACULATORY SPERM CELLS | 2019 |
|
RU2685797C1 |
