FIELD: molecular biology.
SUBSTANCE: what is described is a method for prediction of idiopathic male infertility involving DNA recovery and genotyping of a polymorphic variant rs25487 of the DNA repair system gene (XRCC1). According to the invention, the method employs a native ejaculate produced by way of mastication, and if the genotype GG or allele G of the polymorphic variant rs25487 is detected, a risk of developing idiopathic male infertility in the form of oligoasthenoteratospermia or asthenoteratozoospermia is predicted.
EFFECT: higher prediction accuracy.
1 cl, 1 tbl, 4 ex
Title | Year | Author | Number |
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METHOD OF PREDICTION OF IDIOPATHIC MALE INFERTILITY BASED ON ANALYSIS OF NUCLEOTIDE VARIANTS IN MITOCHONDRIAL CYTOCHROME B GENE | 2022 |
|
RU2800406C1 |
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MALE REPRODUCTIVE FUNCTION TEST METHOD | 2023 |
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RU2819094C1 |
METHOD FOR DETERMINING NEED FOR ASSISTED REPRODUCTIVE TECHNOLOGIES (ART) WITH SPERM DONATION IN IDIOPATHIC MALE INFERTILITY WITH NON-OBSTRUCTIVE AZOOSPERMIA | 2023 |
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RU2814377C1 |
METHOD FOR DIAGNOSING MALE INFERTILITY | 2023 |
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RU2818459C1 |
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RU2685797C1 |
Authors
Dates
2024-09-30—Published
2024-02-20—Filed