METHOD FOR INTRODUCING GOLD NANOPARTICLES BY LOCAL SKIN APPLICATION Russian patent published in 2013 - IPC A61K8/04 A61K8/19 A61K8/46 A61K9/10 A61K31/255 A61K33/00 B82Y5/00 

FIELD: medicine.

SUBSTANCE: invention refers to pharmaceutical industry and represents a method for introducing gold nanoparticles into the body by the local skin application, differing by applying the preparation of the following composition: 96% dimethyl sulphoxide 0.1 ml per a gel base 1 ml with gold nanoparticles d=140 nm, or the preparation of the following composition: 20% thiophane sulphoxide 0.1 ml per a gel base 1 ml with gold nanoparticles d=40 nm; the skin areas coated with gold nanoparticles in complex with organic sulphur compounds shall be exposed to ultrasound at frequency 1 MHz, power 2 Wt and length 2 minutes.

EFFECT: invention provides higher transdermal permeability of gold nanoparticles and no nanoparticle accumulation in the internal organs.

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