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2 707 571

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IPC

G01N33/49(2006-01-01)

G01N33/53(2006-01-01)

(21) (22)

Application

2018136193, 2018-10-12

(24)

Start date

2018-10-12

(22)

Actual filing date

2018-10-12

(45)

Published

2019-11-28

(72)

Inventor

Starshinova Anna AndreevnaZinchenko Yuliya SergeevnaIstomina Evgeniya ViktorovnaFilatov Mikhail ValentinovichDenisova Nina VladimirovnaPavlova Mariya VasilevnaSapozhnikova Nadezhda ValentinovnaYablonskij Petr KazimirovichBurdakov Vladimir StanislavovichChurilov Leonid Pavlovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauchno-Issledovatelskij Institut Ftiziopulmonologii" Ministerstva Zdravookhraneniya Rossijskoj Federatsii Niif" Minzdrava Rossii)Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Universitet"

METHOD FOR PREDICTION OF DEVELOPING TUBERCULOSIS IN HEALTHY INDIVIDUALS Russian patent published in 2019 - IPC G01N33/49 G01N33/53

Abstract RU 2707571 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to a method for prediction of developing tuberculosis in healthy individuals. Method for prediction of development of tuberculosis in healthy people, consisting in carrying out a complex of immunological studies in individuals with positive immunological test results, wherein the prepared blood plasma samples are added with the tuberculosis antigens ESAT-6/SFP-1, followed by the dynamic light scattering method, determining and analyzing the formed immune complexes and their isotypes and with the content of IgG3, IgE, IgG1+IgG3, IgG3+IgE, IgG1+IgE higher than 1.0 % shows the risk of developing tuberculosis.

EFFECT: method described above enables higher prognosis of tuberculosis development to 100 % in individuals with positive immunological tests due to sensitivity and specificity.

1 cl, 6 tbl, 2 ex

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RU 2 707 571 C1

Authors

Starshinova Anna Andreevna

Zinchenko Yuliya Sergeevna

Istomina Evgeniya Viktorovna

Filatov Mikhail Valentinovich

Denisova Nina Vladimirovna

Pavlova Mariya Vasilevna

Sapozhnikova Nadezhda Valentinovna

Yablonskij Petr Kazimirovich

Burdakov Vladimir Stanislavovich

Churilov Leonid Pavlovich

Dates

2019-11-28—Published

2018-10-12—Filed