IMMUNOMODULATING OLIGOPEPTIDES Russian patent published in 2014 - IPC C07K5/08 C07K7/06 A61K38/06 A61K38/08 

Abstract RU 2503684 C2

FIELD: biotechnologies.

SUBSTANCE: invention refers to application of oligopeptide chosen from a group consisting of tripeptide of general formula X-Pro-Tyr (X-P-Y), in which X can be chosen from a group consisting of Ile (I), Val (V), Ala (A), Trp (W), Leu (L), Phe (F), Gly (G), Glu (E) and Asn (N), or peptides including the above tripeptide, in medicine for immunomodulation. Besides, application of the above oligopeptide for production of remedy to be used as an immunomodulator is disclosed. Immunomodulating pharmaceutical composition containing an effective amount of the above oligopeptide, as well as a vaccine containing it are disclosed. Besides, a method for reinforcement of mammal immune system, as well as a method for improvement of immunogenic activity of vaccine composition using the above immunomodulating composition are disclosed. A method providing immunoreactivity to peptide or improvement of peptide immunoreactivity with a peptide compound with the above oligopeptide is disclosed.

EFFECT: use of oligopeptides in medicine for immunomodulation.

19 cl, 2 dwg, 2 tbl, 2 ex

Similar patents RU2503684C2

Title Year Author Number
IMMUNOCYTOKINES BASED ON IL-15 AND IL-15Rα OF THE SUSHI DOMAIN 2012
  • Morisso Sebastyan Danel
  • Teppa Zheraldin
  • Zhak Yannik Loran Zhozef
  • Rober Bruno Zhilber Mark
  • De Martinoff Gi Lyuk Mishel
  • Beshar David
RU2763298C2
COMPOSITIONS OF VACCINES AGAINST NEOPLASIA AND METHODS FOR OBTAINING THEREOF 2016
  • Fritsch, Edward, F.
RU2753246C2
COMBINATION THERAPY OF ANTIBODY TO PROGASTRIN AND IMMUNOTHERAPY FOR CANCER TREATMENT 2018
  • Prier, Aleksandr
RU2784604C2
COMPOSITIONS OF IMMUNOGENIC/THERAPEUTIC GLYCOCONJUGATES AND USE THEREOF 2015
  • Hsieh, Yih, Huang
  • Chen, I, Ju
  • Lee, Wei-Han
  • Wang, Nan-Hsuan
  • Yuj Chen-Der Toni
RU2720295C2
ANTIBODIES TO HUMAN INTERLEUKIN-2 AND THEIR APPLICATION 2018
  • Surh, Charles D.
  • Lee, Jun-Young
RU2745451C1
PEPTIDE OBTAINED FROM DEPDC1 AND VACCINE CONTAINING IT 2016
  • Yamashita, Sachiko
  • Hikichi, Tetsuro
RU2765574C2
VACCINE COMPOSITION FOR TREATMENT OF CANCER 2018
  • Nikosia, Alfredo
  • Skarselli, Elisa
  • D'Alise, Anna Morena
RU2782261C2
CYTOMODULATING LIPOPHILIC PEPTIDES FOR MODULATION OF IMMUNE SYSTEM ACTIVITY AND SUPPRESSION OF INFLAMMATION 1998
  • B'Juehlou Roland
  • Grassi Zherar
  • Kala Bernar
RU2214417C2
ANTIBODY-DRUG CONJUGATES CONTAINING HERBOXYDIENE-BASED SPLICING MODULATOR, AND METHODS OF USE THEREOF 2019
  • Fishkin, Nathan
  • Samarakoon, Thiwanka
  • Palacino, James
  • Arai, Kenzo
  • Kotake, Yoshihiko
  • Okubo, Shinya
  • Murai, Norio
  • Miyano, Masayuki
RU2820607C2
COMPOSITIONS AND METHODS FOR DIAGNOSTICS AND TREATMENT OF TUMOUR 2010
  • Dehnnis Mark
  • Polakis Pol
  • Rubinfeld Bonni
RU2563359C2

RU 2 503 684 C2

Authors

Litvinov Sergej V.

Dates

2014-01-10Published

2007-03-29Filed