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(19)

(11)

2 505 541

(13)

(51)

IPC

C07D489/04(2006-01-01)

C07D489/02(2006-01-01)

A61K31/44(2006-01-01)

A61K31/485(2006-01-01)

A61K47/48(2006-01-01)

A61K9/02(2006-01-01)

A61P25/36(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2012103476/04, 2010-07-01

(24)

Start date

2010-07-01

(22)

Actual filing date

2010-07-01

(45)

Published

2014-01-27

(72)

Inventor

Mikl TrevisGjunter SvenMikl KristehlChi Gochehn'Kan'Ski JaroslavMartin Andrea K.Bera Bindu

(73)

Holder

Kemfarm, Ink.

CONJUGATES OF HYDROCODONE WITH BENZOIC ACID, DERIVATIVES OF BENZOIC ACID AND HETERO-ACRYL-CARBON ACID, PRODRUGS, METHODS FOR THEIR OBTAINING AND APPLICATION Russian patent published in 2014 - IPC C07D489/04 C07D489/02 A61K31/44 A61K31/485 A61K47/48 A61K9/02 A61P25/36 A61P29/00

Abstract RU 2505541 C2

FIELD: biotechnologies.

SUBSTANCE: conjugate represents benzoate-hydrocodone that has the following structure: benzoate-hydrocodone (Bz-HC). Invention also pertains to the application of pharmaceutical compound for obtaining the drug for curing the patient with illness, disease or condition mediated by opioid binding to the opioid receptors of the patient.

EFFECT: improvement of medical treatment efficiency or prevention of drug abuse, drug withdrawal symptoms or pain relief.

10 cl, 11 ex, 4 tbl, 20 dwg

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RU 2 505 541 C2

Authors

Mikl Trevis

Gjunter Sven

Mikl Kristehl

Chi Gochehn'

Kan'Ski Jaroslav

Martin Andrea K.

Bera Bindu

Dates

2014-01-27—Published

2010-07-01—Filed