METHOD OF OBTAINING REAGENT FOR PREPARATION OF TECHNECIUM 99-m LABELLED NANOCOLLOID BASED ON GAMMA-OXIDE OF ALUMINIUM Russian patent published in 2014 - IPC A61K51/12 A61K103/10 B82B3/00 B82Y5/00 

Abstract RU 2512595 C1

FIELD: chemistry.

SUBSTANCE: method includes preparation of mixture, which consists of 1 ml of water suspension, prepared from nanosize powder of Al2O3 gamma-oxide with size of particles 7-10 nm and concentration 0.5-0.7 mg/ml, 0.20-0.25 mg of ascorbic acid, 0.00875-0.0175 mg Sn (II) and 2.5-4.0 mg. Further method includes freezing obtained solution at temperature of liquid nitrogen, placing in chamber of sublimator and lyophilic drying with specified parameters of lyophiliser: T=-50°C, vacuum 0.0015 Torr, for 20.5 hours, with following transfer into upper lyophilic chamber and drying for 5.5 h at temperature +15°C.

EFFECT: obtaining reagent stable in storage.

2 tbl, 1 ex

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Authors

Chojnzonov Evgenij Lkhamatsyrenovich

Chernov Vladimir Ivanovich

Zel'Chan Roman Vladimirovich

Titskaja Anna Aleksandrovna

Sinilkin Ivan Gennad'Evich

Varlamova Natal'Ja Valer'Evna

Stasjuk Elena Sergeevna

Dates

2014-04-10Published

2013-01-09Filed