EYE DEVICE, CAPABLE OF DELIVERING THERAPEUTIC PREPARATION AND METHOD OF OBTAINING THEREOF Russian patent published in 2014 - IPC A61K47/32 A61L27/50 A61F2/16 A61P27/02 

Abstract RU 2519704 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to ophthalmology and is intended for delivery of a therapeutic preparation into an eye. An eye device contains a non-biodegradable mass of material, which includes a hydrophobic component, represented in an amount, sufficient for contact angle of the material to be larger than 50° and formed of at least 80% by weight of acryl material. The device also contains the therapeutic preparation, located on the peripheral surface of the material mass. The therapeutic preparation is hydrophobic and has a coefficient of distribution in the system octane/water PC Log P, equal at least to 1.0. The material mass is formed for introduction into the human eye. Attraction of the therapeutic agent to the hydrophobic part controls a delayed release of the therapeutic preparation in such a way that less than 50 wt % of the therapeutic preparation is released from the eye device into the basic salt solution (BSS) within at least three days. The method of the eye device obtaining includes submergence of the material mass into the solution, which contains a solvent and the therapeutic preparation.

EFFECT: application of the group of inventions ensures delivery of the therapeutic preparation into the eye within long period of time.

19 cl, 12 dwg, 1 tbl, 12 ex

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RU 2 519 704 C2

Authors

Tomz Brett Eh.

Van Noj Stefen Dzh.

Tsaj Chi-Chun

Dates

2014-06-20Published

2009-07-20Filed