DIRECTLY PRESSIBLE AND RAPIDLY-DECOMPOSABLE TABLET MATRIX Russian patent published in 2014 - IPC A61K9/20 A61K9/16 A61K47/10 A61K47/38 

Abstract RU 2519768 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to the general mixture for production of rapidly decomposable tablets in the process of direct tabletting. The claimed mixture contains 90-98 weight parts of the pulverised mannit with water content from 0.3 to 1% by weight and 2-10 weight parts of cross-linked sodium-carboxymethylcellulose. The general mixture has the area of BET surface in the range from 1.5 to 4.0 m2g. The invention also relates to application of the said general mixture for preparation of tablets, including vitamins, mineral substances, microelements, functional food components, plant components and extracts, synthetic and natural dyes and flavours, as well as substances, possessing pharmacological action.

EFFECT: invention relates to the tablet composition, which contains an active compound and/or a flavour, and is prepared with application of the general mixture as a shape-forming material/ The invention ensures facilitation of direct tablet pressing, as well as obtaining tablets with the improved hardness.

14 cl, 1 dwg, 2 ex

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RU 2 519 768 C2

Authors

Daniela Klajnvehkhter

Gjunter Moddel'Mog

Roberto Ognibene

Dates

2014-06-20Published

2009-05-25Filed