ANALYSES Russian patent published in 2014 - IPC B01L3/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: group of inventions relates to versions of a method and a device for performing a sample analysis for different analytes. The method includes contact of a body of separated zones of an analysis with a liquid sample, for instance, with whole blood. The zones of analysis are located inside a channel of a microfluidic device. The channel is formed by at least one flexible wall and the second wall, which can be flexible or not. Each zone of the analysis contains a probe-compound, specific to the respective target analyte. The microfluidic device is compressed to reduce the channel thickness, which represents a distance between internal surfaces of walls inside the channel. The presence of each analyte is determined by means of optic detection of interaction in each of a multitude of the analysis zones, for which the distance between internal surfaces in the respective location is reduced. Interaction in each analysis zone indicates the presence of the target analyte in the sample. Capillary structures of devices or those used in methods can contain a matrix, the devices can contain control elements, and, therefore, the methods of carrying out the sample analysis can apply respective control functions.

EFFECT: providing more accurate qualitative and/or quantitative determination of analytes in the sample.

154 cl, 38 dwg