CAPILLARY-ACTION ANALYTICAL DEVICE AND MANUFACTURE THEREOF Russian patent published in 2015 - IPC G01N33/48 A61B5/00 

FIELD: chemistry.

SUBSTANCE: group of inventions relates to surface hydrophilisation and immobilisation of antibodies on the surface of a cycloolefin copolymer. Disclosed method of making a capillary-action analytical device, which includes steps of: a) providing a capillary substrate, b) changing the hydrophilic property of the surface, c) mixing a matrix and immobilised molecules in solution form to obtain a solution which includes immobilised molecules covalently bonded to the matrix, and d) depositing the solution on a well defined region in at least one storage area. Also a capillary-action analytical device made using said method is described.

EFFECT: enabling change of the substrate by chemical treatment of the surface and depositing immobilised molecules in an optimum matrix on given regions, with less consumption of matrix material, which enables to use several different matrix material in the same chip.

33 cl, 3 dwg