FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine and concerns methods for creation a tooth of a required size, and repair of the lost teeth in the oral cavity by transplantation of the created tooth into the dental loss. Particularly, the method for the tooth creation of a required length in one direction involves the stages: placing the first cell aggregate and the second cell aggregate in a tight contact inside a supporting carrier, wherein the first cell aggregate and the second cell aggregate respectively consists of mesenchymal or epithelial cells; culturing the first and second cell aggregate inside the supporting carrier; the tooth size is corrected by a contact length of the first cell aggregate and the second cell aggregate in the same pre-set direction. A method for determining the contact length of the first and second cell aggregate for the tooth preparation of the required size involves preparing a number of structural types containing structures of various contact length of the first and second cell aggregate in the same pre-set direction; culturing each of a number of structural types inside the supporting carrier; measuring the tooth length prepared at the previous stage in one direction; correlating the given length and contact length providing the basis for calculating the required contact length of the first cell aggregate and the second cell aggregate.
EFFECT: group of inventions enables creating the tooth of the required size that enables preparing a single tooth that can be used as it is in the form of a transplant.
23 cl, 1 tbl, 6 ex, 13 dwg
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METHOD OF INDUCING SPONTANEOUS DIFFERENTIATION OF CELLS OF PERIODONTAL LIGAMENT AND PERIOSTEUM IN ODONTOGENIC AND OSTEOGENIC DIRECTIONS BY USING A DECELLULARIZED MATRIX OF TOOTH AND HUMAN PERIODONTAL LIGAMENT | 2022 |
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Authors
Dates
2014-07-20—Published
2010-01-14—Filed