FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to biotechnology and medicine, namely to agents possessing an inhibitory action of opportunistic bacteria, particularly on Escherichia coli O75 No. 5557 bacteria. The invention represents an agent inhibiting growth and bacterial activity of opportunistic Escherichia coli O75 No. 5557 of mixed amino acids containing 1.0-2.0 mcg/ml of serine, 1.0-2.0 mcg/ml of methionine, 0.5-1.5 mcg/ml of alanine, 0.5-1.5 mcg/ml of glycine, water - the rest. The best results have been obtained when using the agent containing: 1.1 mcg/ml of serine, 1.5 mcg/ml of methionine, 0.9 mcg/ml of alanine, 0.8 mcg/ml of glycine, water - the rest. The inhibitory action of the above composition may be increased if adding anions of formic, acetic and lactic acids to the formulation in the following proportions: 1.0-2.0 mcg/ml of serine, 1.-2.0 mcg/ml of methionine, 0.5-1.5 mcg/ml of alanine, 0.5-1.5 mcg/ml of glycine, 80.0-100.0 mcg/ml of sodium lactate, 20.0-30.0 mcg/ml of sodium formate, 400.0-450.0 mcg/ml of sodium acetate, water - the rest (Version 2). The best results have been obtained when using the composition containing: 1.1 mcg/ml of serine, 1.5 mcg/ml of methionine, 0.9 mcg/ml of alanine, 0.8 mcg/ml of glycine, 89.7 mcg/ml of sodium lactate, 27.2 mcg/ml of sodium formate, 410.4 mcg/ml of sodium acetate, water - the rest. The declared composition has been coded as Composition O75.
EFFECT: invention enables preparing the compositions having the inhibitory effect of bacterial activity of Escherichia coli O75 No 5557 cells, particularly on their growth and pathogenic activity.
4 cl, 2 dwg, 4 tbl, 6 ex
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