METHOD FOR SELECTING THERAPEUTIC APPROACH TO LOCALLY ADVANCED PROSTATE CANCER Russian patent published in 2014 - IPC A61N5/10 A61K38/09 A61K38/22 A61P35/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: blood prostate specific antigen is measured. Radiation therapy is carried out, and Zoladex 3.6 mg is administered every 28 days before, during and after radiation. If the blood PSA is lower than 1 ng/ml three months after the beginning of the Zoladex therapy, administering the preparation is continued for the following 6 months. Radiation therapy involves a split course in the regimen of the common radiation dose fractionation to the total radiation dose 64 Gy. If the blood PSA is found to be below 1 ng/ml only six months after the beginning of the Zoladex therapy, administering the preparation is continued for the following 9 months. Radiation therapy involves the split course in the regimen of the common radiation dose fractionation to the total radiation dose 70 Gy. If the blood PSA is above 1 ng/ml six months later, Zoladex is administered in a combination with Casodex 50 mg administered daily for the following 12 months. Radiation therapy involves the split course in the regimen of the common radiation dose hypofractionation to the total radiation dose 70 Gy.

EFFECT: higher effectiveness and optimisation of treatment, substantial reduction of a number of complications on the part of a wide range of a patient's body systems, and prolonged remission.

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