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IPC

G09B23/28(2006-01-01)

A61K31/05(2006-01-01)

A61K35/64(2006-01-01)

A61P9/08(2006-01-01)

(21) (22)

Application

2013101734/14, 2013-01-14

(24)

Start date

2013-01-14

(22)

Actual filing date

2013-01-14

(45)

Published

2014-08-10

(72)

Inventor

Pokrovskij Mikhail VladimirovichGribanov Nikolaj NikolaevichPokrovskaja Tat'Jana Grigor'EvnaArustamova Anna AleksandrovnaZatolokina Marija AlekseevnaKochkarov Vladimir IskhakovichKorokin Mikhail ViktorovichGudyrev Oleg Sergeevich

(73)

Holder

Federal'Noe Gosudarstvennoe Avtonomnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Natsional'Nyj Issledovatel'Skij Universitet"Obshchestvo S Ogranichennoj Otvetstvennost'Ju Ob"Edinenie

METHOD FOR ENDOTHELIAL PROTECTION WITH API-PHYTOCOMPOSITION Russian patent published in 2014 - IPC G09B23/28 A61K31/05 A61K35/64 A61P9/08

Abstract RU 2524799 C1

FIELD: medicine.

SUBSTANCE: method involves simulating endothelial dysfunction in Wistar male rats by daily intraperitoneal introduction of L-nitro-arginine-methyl ester 25 mg/kg/day for 7 days. Endothelial dysfunction is corrected by intragastric introduction of an api-phytocomposition in the form of an aqueous suspension of honey, royal jelly, bee bread, Resveratrol in the ratio of 10:1:1:2. The composition is introduced in a dose of 200 mg/kg of an animal's body weight once a day for 7 days.

EFFECT: method provides synergetic endothelioprotective effects with no side effects observed when treating with synthetic preparations.

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RU 2 524 799 C1

Authors

Pokrovskij Mikhail Vladimirovich

Gribanov Nikolaj Nikolaevich

Pokrovskaja Tat'Jana Grigor'Evna

Arustamova Anna Aleksandrovna

Zatolokina Marija Alekseevna

Kochkarov Vladimir Iskhakovich

Korokin Mikhail Viktorovich

Gudyrev Oleg Sergeevich

Dates

2014-08-10—Published

2013-01-14—Filed