FIELD: medicine.
SUBSTANCE: modeling of ADMA-like model of gestosis in laboratory pregnant rats of Wistar line is carried out by daily introduction of inhibitor of NO-synthase L-NAME in dose 25 mg/kg from 14 to 20 day of pregnancy. Correction of endothelial dysfunction is performed by L-norvalin, which at the background of modeling is introduced intragastrically daily for 7 days in dose 10 mg/kg once per day.
EFFECT: method leads to expressed dysfunction correction under conditions of specific mechanisms of pathological process course in pregnant women.
1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR ENDOTHELIOPROTECTION IN ADMA-SIMILAR GESTOSIS MODEL BY ARGINASE II INHIBITOR | 2016 |
|
RU2639415C1 |
| METHOD OF ENDOTHELIAL DYSFUNCTION CORRECTION IN ADMA-LIKE MODEL OF PREECLAMPSIA USING DETRALEX | 2019 |
|
RU2723453C1 |
| METHOD FOR PLACENTAL MICROCIRCULATION DISORDER CORRECTION IN ADMA-LIKE GESTOSIS MODEL | 2010 |
|
RU2453000C1 |
| METHOD OF ENDOTHELIAL DYSFUNCTION CORRECTION IN AN ADMA-LIKE MODEL OF PREECLAMPSIA USING ACETYLSALICYLIC ACID | 2019 |
|
RU2721290C1 |
| METHOD FOR ENDOTHELIAL DYSFUNCTION CORRECTION WITH AZITHROMYCIN IN ADMA-LIKE GESTOSIS MODEL IN EXPERIMENT | 2012 |
|
RU2507595C2 |
| METHOD FOR CORRECTION OF ENDOTHELIAL DYSFUNCTION OF PHARMACOLOGICAL PRE-CONDITIONING BY NICORANDIL IN SIMULATED ADMA-LIKE GESTOSIS EXPERIMENTALLY | 2014 |
|
RU2543359C1 |
| METHOD FOR ENDOTHELIAL DYSFUNCTION CORRECTION WITH POLYVITAMIN-MINERAL COMPLEX IN ADMA-LIKE GESTOSIS MODELS IN EXPERIMENT | 2011 |
|
RU2460149C1 |
| METHOD FOR ENDOTHELIAL DYSFUNCTION CORRECTION IN ADMA-LIKE GESTOSIS MODEL IN EXPERIMENT | 2012 |
|
RU2507594C2 |
| METHOD FOR ENDOTHELIAL DYSFUNCTION CORRECTION BY RECOMBINANT ERYTHROPOIETIN IN ADMA-LIKE GESTOSIS MODEL | 2011 |
|
RU2462766C1 |
| METHOD FOR ENDOTHELIAL DYSFUNCTION CORRECTION BY DISTANT PRECONDITIONING IN ADMA-LIKE GESTOSIS MODEL | 2011 |
|
RU2462765C1 |
