Show metadata Hide metadata

(19)

(11)

2 525 663

(13)

(51)

IPC

C12N1/20(2006-01-01)

C12N5/07(2010-01-01)

(21) (22)

Application

2013109193/10, 2013-03-04

(24)

Start date

2013-03-04

(22)

Actual filing date

2013-03-04

(45)

Published

2014-08-20

(72)

Inventor

Vetchinin Sergej SergeevichPavlov Vitalij MikhajlovichGalkina Elena VjacheslavovnaVakhrameeva Galina MikhajlovnaGrishaeva Nadezhda SergeevnaMokrievich Aleksandr NikolaevichDjatlov Ivan Alekseevich

(73)

Holder

Federal'Noe Bjudzhetnoe Uchrezhdenie Nauki Gosudarstvennyj Nauchnyj Tsentr Prikladnoj Mikrobiologii I Biotekhnologii Gnts Pmb)

STRAIN OF HYBRID CULTURED ANIMAL CELLS Mus musculus 2F9-PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC FOR LYSOSTAPHIN AND INHIBITING ITS LYTIC ACTIVITY Russian patent published in 2014 - IPC C12N1/20 C12N5/07

Abstract RU 2525663 C1

FIELD: biotechnology.

SUBSTANCE: new strain of hybrid cultured animal cells Mus musculus 2F9 - producer of monoclonal antibodies specific for lysostaphin inhibiting its lytic activity and suitable for its quantitation is proposed. High-affinity monoclonal antibodies (mAb) of hybridoma 2F9 enables to determine lysostaphin in the samples to the concentrations of 0.8 ng/ml. The mAb of hybridoma 2F9 can be used to study the structural and functional properties of lysostaphin and quality control of preparations based on lysostaphin.

EFFECT: improved properties.

3 dwg, 1 tbl, 5 ex

Similar patents RU2525663C1

Title	Year	Author	Number
STRAIN OF HYBRID CULTIVATED ANIMAL CELLS Mus museums 2E4-PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO HEAT SHOCK PROTEIN 70	2008	Vetchinin Sergej Sergeevich Belova Elena Valentinovna Baranov Andrej Mitrofanovich Sapozhnikov Aleksandr Mikhajlovich Margulis Boris Aleksandrovich	RU2381271C1
STRAIN OF HYBRID CULTIVATED ANIMAL CELLS Mus musculus A 6G2-PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO HEAT SHOCK PROTEIN 70	2008	Vetchinin Sergej Sergeevich Nikolaeva Ol'Ga Germanovna Galkina Elena Vjacheslavovna Sapozhnikov Aleksandr Mikhajlovich Margulis Boris Aleksandrovich	RU2380413C1
STRAIN OF THE HYBRID CULTURED MAMMALIAN CELLS MUS MUSCULUS L - A PRODUCER OF MONOCLONAL ANTIBODIES TO A-DETERMINANT OF HEPATITIS B VIRUS SURFACE ANTIGEN	1994	Ammosov A.D. Rukavishnikov M.Ju. Poryvaeva V.A.	RU2097426C1
STRAIN OF HYBRID CULTURED ANIMAL CELLS MUS MUSCULUS L - A PRODUCER OF MONOCLONAL ANTIBODIES RAISED TO A-DETERMINANT OF HEPATITIS B VIRUS SURFACE ANTIGEN	1994	Ammosov A.D. Rukavishnikov M.Ju. Poryvaeva V.A.	RU2092553C1
STRAIN OF THE HYBRID CULTURED MAMMALIAN CELLS MUS MUSCULUS L - A PRODUCER OF MONOCLONAL ANTIBODIES TO A-DETERMINANT OF HEPATITIS B VIRUS SURFACE ANTIGEN	1994	Ammosov A.D. Rukavishnikov M.Ju. Poryvaeva V.A.	RU2097425C1
STRAIN OF HYBRID CULTURED CELLS OF ANIMAL MUS MUSCULUS L FOR PREPARING MONOCLONAL ANTIBODIES RAISED TO PROTEIN 105 KDA OF EXCRETORY-SECRETORY ANTIGEN OF HUMAN HEPATIC TREMATODE OPISTHORCHIS FELINEUS	1997	Kotelkin A.T. Razumov I.A. Loktev V.B.	RU2143488C1
STRAIN OF HYBRID CULTURED MAMMALIAN CELLS MUS MUSCULUS L - A PRODUCER OF MONOCLONAL ANTIBODIES SHOWING SPECIFICITY TO BRUCELLA PROTEIN PREPARATION OF MOLECULAR MASS 18 AND 38 KDA	1996	Mikhajlov L.M. Titenko A.M. Zakhlebnaja O.D. Laukner I.V.	RU2113475C1
STRAIN OF HYBRIDOUS CULTURED CELLS MUS MUSCULUS L, USED FOR PREPARATION OF MONOCLONAL ANTIBODIES TO THE GENERAL ANTIGENIC DETERMINANT OF HUMAN AND SIMIAN ALPHA-1-ANTITRYPSIN	0	Samilchuk Elena Ivanovna Sarsaniya Zhanna Shalvovna Khadzhirisyan Marina Leonovna Zodelava Irina Grigorevna	SU1756352A1
HYBRID CELL STRAIN OF Mus. musculus ANIMALS - PRODUCER OF MONOCLONAL IVERMECTIN ANTIBODIES, AND MONOCLONAL IVERMECTIN ANTIBODIES	2009	Tarasov Il'Ja Evgen'Evich Kostina Ljudmila Vladimirovna Tsibezov Valerij Vladimirovich Kozlov Aleksej Jur'Evich Nepoklonov Anatolij Aleksandrovich Aliper Taras Ivanovich Verkhovskij Oleg Anatol'Evich	RU2415930C1
STRAIN OF HYBRIDOUS CULTURED MAMMALIAN CELLS MUS MUSCULUS L - PRODUCER OF MONOCLONAL ANTIBODIES TO BACTERIA OF BRUCELLA GENUS	0	Bulashev Ajtbaj Kabykeshovich Eskendirova Saule Ziyadinovna Dmitriev Anatolij Fedorovich Borovikov Sergej Nikolaevich Shenzhanov Kanat Tyulyubaevich	SU1752764A1

RU 2 525 663 C1

Authors

Vetchinin Sergej Sergeevich

Pavlov Vitalij Mikhajlovich

Galkina Elena Vjacheslavovna

Vakhrameeva Galina Mikhajlovna

Grishaeva Nadezhda Sergeevna

Mokrievich Aleksandr Nikolaevich

Djatlov Ivan Alekseevich

Dates

2014-08-20—Published

2013-03-04—Filed