COMBINED GRAFT OF DERMAL MATRIX WITH MESENCHYMAL MULTIPOTENT STROMAL CELLS, METHOD FOR PREPARING IT AND METHOD FOR WOUND HEALING USING IT Russian patent published in 2014 - IPC A61K35/36 C12N5/775 A61P17/02 

Abstract RU 2526813 C1

FIELD: medicine.

SUBSTANCE: combined graft (CG) represents a dermal matrix (DM) prepared of a donor layer with self-specific multipotent mesenchymal stromal cells (MMSC) colonised on the surface thereof to the number of not less than 750-1500 thousand per 1 cm2. The group of inventions also refers to a method for preparing the combined graft involving bone marrow sampling from the patient, preparing a MMSC culture, applying a MMSC suspension in the concentration of not less than 1 million/ml on the DM surface at 1 million MMSC per 5 cm2 of the DM.

EFFECT: skin and soft tissue wound healing by accelerating regeneration processes.

11 cl

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RU 2 526 813 C1

Authors

Khubutija Mogeli Shalvovich

Borovkova Natal'Ja Valer'Evna

Filippov Oleg Petrovich

Pokhitonov Dmitrij Jur'Evich

Kljukvin Ivan Jur'Evich

Khvatov Valerij Borisovich

Ponomarev Ivan Nikolaevich

Zhirkova Elena Aleksandrovna

Shugaj Svetlana Viktorovna

Andreev Julij Vadimovich

Dates

2014-08-27Published

2013-04-16Filed