METHOD OF PREDICTING LOWER EXTREMITY AMPUTATION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND ATHEROSCLEROSIS, COMPLICATED BY ULCEROUS INJURY OF FOOT Russian patent published in 2014 - IPC A61B5/01 

FIELD: FUELD: medicine.

SUBSTANCE: invention relates to medicine, namely to surgery, and can be applied for the prediction of the lower extremity amputation in patients with type 2 diabetes mellitus and atherosclerosis, complicated by ulcerous injury of feet. For this purpose a thermal sensor is applied on skin of a palm surface of the distal phalange of 2 finger of the examined person's right hand. Temperature at rest is measured for 10 minutes. Then, with continuous registration of the temperature, an indirect cold test is carried out with immersion of the left hand into a basin a with water-ice mixture at a temperature of 0°C for 3 minutes. When they expire, the left hand is taken out and measuring of the skin temperature is continued for 3 minutes after the cold test. The obtained temperature results are transformed into amplitudes of oscillations by wavelet analysis in the range of frequencies of 0.02-0.05 Hz. Results are fixed on 10-th minute before the test and on 13-th minute after finishing the cold test. Then, dynamics of the temperature oscillation amplitude (A) is evaluated by a certain mathematic formula. If A value is lower than 0.00001 carrying out amputation of the affected lower extremity in future is predicted.

EFFECT: method makes it possible to predict development of life-threatening complications of diabetic foot syndrome in the remote period of time and if necessary to start pathogenically justified therapy at a proper time.

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