METHOD FOR PREDICTION OF NON-DEVELOPING PREGNANCY Russian patent published in 2014 - IPC G01N33/50 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to obstetrics and gynaecology, and can be used for the prediction of a non-developing pregnancy (NP). Substance of the method: uterine or menstrual aspirate supernatant is examined for carbonyl groups of protein and malondialdehyde at the same time. If the values of the carbonyl groups are 9.43 to 16.91 nmole/ml, and the values of malodialdehyde are 0.71 mcmole/l to 7.28 mcmole/l of malonaldehyde, they are stated to have no negative effect on the endometrium and the gestational sac. If the values of the carbonyl groups fall within the range of 22.32 nmole/mg and more, and if the values of malondialdehyde exceed 7.28 mcmole/l, their negative effect on the gestational sac and a high risk of a non-developing pregnancy are stated. The invention aims at optimising the method for the prediction of a non-developing pregnancy at the pre-clinical stage, at the preventing the negative effect of oxidative stress products on the endometrium at the stage of pre-conceptional preparation.

EFFECT: method is characterised by low invasiveness, technical simplicity, accessibility in women's health clinics and hospitals.

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