METHOD FOR VACCINAL PREVENTION OF RESPIRATORY DISEASES IN CALVES Russian patent published in 2014 - IPC A61K39/295 A61P11/00 A61P31/12 

FIELD: medicine.

SUBSTANCE: invention refers to veterinary immunology. A method for the vaccinal prevention of respiratory diseases in calves involves immunising 20-30-day-old clinically healthy calves three times every 10-12 days by subcutaneous injections of animal donor's hyperimmune serum containing anti-parainfluenza virus type 3 hemagglutinin antibodies in titre min. 1:1280, anti-rednose virus hemagglutinin antibodies in titre min. 1:256, anti-viral diarrhoea virus hemagglutinin antibodies in titre min. 1:1024, anti-respiratory syncytial virus hemagglutinin antibodies in titre min. 1:128, anti-rotavirus and anti-coronavirus hemagglutinin antibodies in titre min. 1:128, in a dose of 1 ml/kg of body weight; 15 days after the last injection, the animals are vaccinated by double administration of the inactivated combined vaccine Combovac for rednose, parainfluenza type 3, viral diarrhoea, respiratory syncytial, rota- and coronavirus diseases according to the instructions.

EFFECT: method provides higher postvaccinal immunity and the stimulated antibody production as a result of activating cell and humoral immunity and optimising the natural body resistance.

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