BIOINTEGRATED COMPOSITE AND METHOD FOR COATING FORMATION ON MEDICAL DEVICES WITH USE OF BIOINTEGRATED COMPOSITE Russian patent published in 2014 - IPC A61L31/10 A61L31/16 A61C8/00 

FIELD: medicine.

SUBSTANCE: what is described is a biointegrated composite containing the following ingredients, wt %: collagen 5%-10%, polyazolidine ammonia modified by halogen hydrate ions 0.5%-4%, water dispersion of sub-micron flavonoid aggregates 0.5%-1%, water - the rest. What is described is a method for the coating formation, which consists in applying the biologically active composite by immersion or deposition followed by lyophilisation. The drying process is single-staged at a temperature of 3-5°C and pressure of 5×10^-1 Pa. What is also described is a method for administering the biodegradable composite into a bone cavity by separating a mucoperiosteal flap of the operated portion of the alveolar process by special taps, burs and drills forming a bone bed to be filled with a targeted osteointegration substance, mounting an implant, placing back the flap and closing the wound.

EFFECT: composite has biocompatibility and haemocompatibility, optimal physical-chemical properties, as well as rapid resorbability in vivo with generating no toxic products and negative reactions when in use.

3 cl, 9 dwg, 2 tbl, 4 ex