FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to biochemistry and represents a method for producing cysteine involving culturing a recombinant microorganism with the low activity of endogenous phosphoserin phosphatase (SerB) for producing O-phosphoserin (OPS) and contacting the prepared culture containing OPS, or OPS recovered from the culture with sulphide in the presence of O-phosphoserin sulphhydrilase (OPSS) or a microorganism expressing OPSS for preparing cysteine with the recombinant microorganism representing a recombinant bacteria. The invention refers to preparing a cysteine derivative which provides preparing cysteine as presented above to be transformed into the cysteine derivative.
EFFECT: invention enables producing cysteine and its derivative with high efficacy.
31 cl, 6 dwg, 35 tbl, 49 ex
Title |
Year |
Author |
Number |
MICROORGANISM PRODUCING O-PHOSPHOSERINE AND METHOD FOR PRODUCING O-PHOSPHOSERINE OR L-CYSTEINE USING THIS MICROORGANISM |
2015 |
- Kim Sol
- Yoo In Hwa
- Chang Jin Sook
- Kim Hye Won
|
RU2663726C1 |
NEW VERSION OF EFFLUX PROTEIN OF O-PHOSPHOSERINE AND METHOD FOR PRODUCING O-PHOSPHOSERINE, CYSTEINE AND ITS DERIVATIVE USING THIS EMBODIMENT |
2016 |
- Kim Sol
- Kang Min Gyeong
- Yoo In Hwa
- Kim Jong Hyun
- Kim Hye Won
|
RU2694589C1 |
PRODUCTION OF CYSTEINE OR ITS DERIVATIVE WITH APPLICATION OF NEW O-PHOSPHOSERINESULPHHYDRILASE |
2012 |
- Song Byeong Cheol
- Chang Jin Sook
- Jo Jae Hyun
- Kim Hye Won
|
RU2579689C1 |
VERSION OF O-PHOSPHOSERINE EXPORTING PROTEIN, AND METHOD OF PRODUCING O-PHOSPHOSERINE, CYSTEINE AND DERIVATIVES THEREOF USING SAME |
2021 |
- Park Hye Min
- Kim So-Yeon
- Sim Hee-Jin
- Lee Jin Nam
|
RU2821317C1 |
MUTANT O-PHOSPHOSERINE SULFHYDRYLASES AND METHOD OF PRODUCING CYSTEINE USING SAME |
2011 |
- Shin, Soo An
- Chang, Dzin Sook
- Um, Khie Von
- Dzo, Dzae Khiun
- Song, Bieong Cheol
- Li, Kioung Min
|
RU2541782C2 |
MICROORGANISM OF ESCHERICHIA GENUS PRODUCING O-PHOSPHOSERINE AND METHOD OF PRODUCING O-PHOSPHOSERINE OR L-CYSTEINE USING SAID MICROORGANISM |
2017 |
- Sim Se Hoon
- Kim Seo-Yun
- Kim Sol
- Kim Hye Won
- Yoo Inhwa
|
RU2732227C1 |
L-AMINO ACID PRODUCING MICROORGANISM AND METHOD FOR PRODUCING L-AMINO ACID WITH ITS USE |
2020 |
- Yoo Hye Ryun
- Kim So-Yeon
- Park Hye Min
- Lee Sung Gun
- Lee Jin Nam
- Kim Hyun Ah
- Choi Sol
- Huh Lan
|
RU2795161C1 |
NEW PROMOTER AND APPLICATION THEREOF |
2019 |
- Bae Jee Yeon
- Seo Chang Il
- Yoo Inhwa
- Yoo Hye Ryun
- Kim So Young
- Shin Yong Uk
|
RU2756563C1 |
NOVEL O-ACETYLHOMOSERINE-SULPHHYDRILASE OR ITS MUTANT PROTEIN AND METHOD FOR CONVERSION ONTO METHIONINE WITH THEREOF APPLICATION |
2011 |
- Kim So Joung
- Sin Jong Juk
- Seo Chang Il
- Son Sung Kvang
- Kheo In Kiung
- Li Khan Dzin'
- Kim Dzu Eun
- Kim Khiun Akh
- Bae Dzee Jeon
- Na Kvang Kho
|
RU2573928C2 |
MICROORGANISM OF GENUS Escherichia, HAVING ENHANCED ABILITY TO PRODUCE L-TRYPTOPHAN, AND METHOD OF PRODUCING L-TRYPTOPHAN USING SAME |
2013 |
- Li Kvang Kho
- Park Khie Min
- Li Khio Khioung
- Khvang Joung Bin
- Li Seok Miung
|
RU2593957C2 |