FIELD: biotechnology; biochemistry.
SUBSTANCE: invention relates to the field of biochemistry and biotechnology, in particular to the microorganism producing O-phosphoserine. Said microorganism is characterized in that in it the activity of a polypeptide capable of exporting O-phosphoserine and having the SEQ ID NO amino acid sequence: 1 or SEQ ID NO: 2, is enhanced in comparison with its endogenous activity. Invention also relates to a process for the preparation of O-phosphoserine. Present method includes culturing said microorganism in a medium and isolating O-phosphoserin from a microorganism or from a medium. Invention relates to a process for the preparation of cysteine or a derivative thereof. This method involves the preparation of O-phosphoserine by culturing said microorganism in a medium and the interaction of O-phosphoserine with a sulfide in the presence of O-phosphoserine sulfhydrylase or a microorganism capable of its expression.
EFFECT: present invention makes it possible to obtain O-phosphoserine and cysteine in high yield.
8 cl, 1 dwg, 6 tbl, 4 ex
