METHOD FOR FUNCTIONALISING SURFACE OF MAGNETIC NANOPARTICLES Russian patent published in 2015 - IPC G01N33/553 B82B1/00 B82Y5/00 

Abstract RU 2543631 C2

FIELD: chemistry.

SUBSTANCE: according to the method magnetic nanoparticles and glutaric dialdehyde are added to a polymer in a phosphate buffer under conditions of an alternating magnetic field, then, peptised and activated particles are three times washed with a phosphate buffer solution, depositing them under the influence of a constant magnet, the activated particles are mixed with an anti-analite solution for conjugation under conditions of the alternating magnetic field, after which the conjugate is washed three times by deposition-resuspension in the phosphate buffer solution, alternating the action of constant and alternating magnetic fields.

EFFECT: obtaining strong functional conjugates which can serve as a basis for the creation of effective instrument-free systems for simplified diagnostic testing.

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RU 2 543 631 C2

Authors

Raev Mikhail Borisovich

Bochkova Marija Stanislavovna

Khramtsov Pavel Viktorovich

Tjulenev Aleksej Valer'Evich

Dates

2015-03-10Published

2013-07-23Filed