FIELD: chemistry.
SUBSTANCE: invention relates to 1-R-4,9-dioxo-1H-naptho[2,3-d][1,2,3]triazole-4-oxim-2-oxides, which have cytotoxic activity, of general formula 1 
, where R=Alk, benzyl; X=H, -C(=O)R', where R'=methyl, phenyl.
EFFECT: novel biologically active compounds are obtained.
1 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR THE PREPARATION OF 1-(2-PROPARGYL)-1H-NAPHTHO[2,3-d][1,2,3]TRIAZOLE-4,9-DIONE-4-OXIME-2-OXIDE | 2022 |
|
RU2791249C1 |
| METHOD FOR PRODUCING NAPHTHO[1,2,3-cd]INDOL-6(2H)-ONES | 2013 |
|
RU2552521C2 |
| METHOD FOR PRODUCING NAPHTHO[1,2,3-cd]INDOL-6(2H)-ONES | 2013 |
|
RU2552416C2 |
| DERIVATIVE OF THE CLASS OF N-GLYCOSIDES INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE-5,7-DIONE - N-{12-(β-D-XYLOPYRANOSYL)-5,7-DIOXO-INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOL-6-YL} PYRIDINE-2-CARBOXAMIDE, WHICH HAS CYTOTOXIC AND ANTITUMOR ACTIVITY | 2017 |
|
RU2667906C1 |
| LABDANE-TYPE 6-HYDROXYNAPHTHOQUINONES, HAVING CYTOTOXIC ACTIVITY ON HUMAN TUMOUR CELLS | 2012 |
|
RU2479582C1 |
| N-GLYCOSIDES OF INDOLO[2,3-a]PYRROLO[3,4-c]CARBAZOLES HAVING ANTITUMOUR ACTIVITY | 2014 |
|
RU2548045C1 |
| METHOD FOR PRODUCING AMINO ACID ANALOGUES OF THE ANTITUMOUR ANTIBIOTIC REBECCAMYCIN | 2020 |
|
RU2755572C1 |
| INDOLOCARBAZOLE DERIVATIVE BLOCKING TUMOUR VASCULOGENIC MIMICRY | 2014 |
|
RU2557554C1 |
| 7-TRIAZOLYL-SUBSTITUTED HYDROXYSPYROSTANES WITH CYTOTOXIC ACTIVITY AGAINST HUMAN TUMOR CELLS | 2023 |
|
RU2798105C1 |
| (E)-2-(4-{ [3-(2,4-DIMETHOXYPHENYL)ACRYLAMIDO]METHYL} -1H-1,2,3-TRIAZOLE-1-YL)-2-ISOPROPYL-9-(4-METHYL PIPERAZINE-1-YL)-3,7-DIOXO-3,7-DIHYDRO-2H-FURO[3,2-g]CHROMEN, HAVING ANALGESIC ACTIVITY | 2014 |
|
RU2549574C1 |
