FIELD: medicine.
SUBSTANCE: membrane-bound red cell haemoglobin by giant combined diffusion (GCD) spectroscopy is analysed by the use of nanostructured coatings in the form of ring silver nanostructures having the hierarchical structure. Silver ring rims consists of connected micron-scale porous silver aggregates, the surface of which comprises rounded silver nanoparticles 2-100nm embedded into a matrix. The red cell immobilisation time on the nanostructured coatings makes 5-40 minutes, and GCD spectra are generated by green laser at wave length 514 or 532 nm.
EFFECT: invention enables diagnosing membrane-bound haemoglobin in undamaged red cells by the giant combined diffusion.
4 cl, 4 ex, 1 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF ANALYSING CYTOCHROME C IN INTACT MITOCHONDRIA BY GIANT COMBINED DIFFUSION SPECTROSCOPY ON NANOSTRUCTURED COATINGS | 2014 |
|
RU2585118C2 |
| PLANAR SOLIDPHASE OPTICAL SENSOR FOR DETERMINATION OF PROTEIN COMPOUNDS BY THE METHOD OF SPECTROSCOPY OF GIANT RAMAN SCATTERING AND ITS APPLICATION FOR PROTEIN COMPOUNDS DETECTION | 2016 |
|
RU2659987C2 |
| METHOD FOR FABRICATING SUBSTRATES FOR GIANT RAMAN SPECTROSCOPY | 2022 |
|
RU2797004C1 |
| METHOD FOR DETERMINING PROTEINS USING GIANT RAMAN SCATTERING USING CRYOSOLS OF PLASMON NANOPARTICLES | 2019 |
|
RU2717160C1 |
| METHOD OF DETECTING AND DETERMINING DNA WITH A GIVEN SEQUENCE USING GIANT RAMAN SCATTERING SPECTROSCOPY | 2019 |
|
RU2723160C1 |
| PLANAR NANOSTRUCTURED SENSOR BASED ON SURFACE PLASMON RESONANCE TO ENHANCE RAMAN LIGHT SCATTERING OF HUMAN PLATELETS AND METHOD FOR ITS PRODUCTION | 2022 |
|
RU2788479C1 |
| CHEMICALLY MODIFIED PLANAR OPTICAL SENSOR, METHOD OF MAKING SAME AND METHOD OF ANALYSING POLYAROMATIC HETEROCYCLIC SULPHUR-CONTAINING COMPOUNDS USING SAME | 2015 |
|
RU2572801C1 |
| USE OF HYBRID SUBSTRATES OF SILICON NANOWIRES DECORATED WITH SILVER AND/OR GOLD NANOPARTICLES FOR RAPID DETECTION OF EXPLOSIVES | 2023 |
|
RU2821710C1 |
| SET FOR THE DIAGNOSIS OF BLADDER CANCER USING C228T AND C250T MUTATIONS IN THE hTERT GENE PROMOTER AND THE METHOD FOR ITS IMPLEMENTATION | 2020 |
|
RU2764807C1 |
| METHOD FOR PRODUCING COMPOSITE NANOSTRUCTURES: SILICON DIOXIDE - SILVER | 2017 |
|
RU2643697C1 |
