FIELD: chemistry.
SUBSTANCE: present invention relates to a method of sealing granules, a method of detecting a target molecule, an array, a kit and a device for detecting a target molecule. The method includes (i) a step of feeding a hydrophilic solvent (42) containing granules (40), (41') into space (30) between (a) part of a lower layer (10), which includes a plurality of craters (13), each capable of storing only one granule (41), (41') and which are separated from each other by a side wall (12), having a hydrophobic top surface, and (b) part of an upper layer (20), facing the surface of part of the lower layer (10) on which the plurality of craters (13) are located. The method also includes (ii) a step of feeding a hydrophobic solvent (43) into space (30), wherein step (ii) is carried out after step (i).
EFFECT: high sensitivity of detecting a target molecule with low concentration.
11 cl, 8 dwg
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|
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