METHOD OF SIGNAL LYMPH NODE BIOPSY IN PATIENTS WITH BREAST CANCER Russian patent published in 2015 - IPC A61B6/03 A61K51/12 G01T1/00 A61B17/00 

FIELD: medicine.

SUBSTANCE: method is carried out by means of an optic navigation system with an intra-tumour introduction of a labelled colloidal radiopharmaceutical (RP), for which purpose dynamic scintigraphy of axillary, parasternal, supra and sub-clavian lymph nodes is carried out from the side of the mammary gland tumour localisation 3-5 min after RP introduction. It is repeated within 20-30 min with a 5-10 min interval. The moment of appearance of the first RP-accumulating node is identified and regarded as SLN. At the moment of appearance of the scintigraphic SLN image 4-5 markers of labels, used in the registration of the navigation system are applied on the patient's skin with positioning: the first marker - in the zone of the humeral head, the second - on lin. ax. anterior in such a way that it does not prevent in performing the biopsy but remains accessible for registration before the operation beginning, the third - at the presternum base, the fourth - 3-5 cm below the third one. In case of the fifth marker fixation its position is not rigidly regulated. Simultaneously SLN topography is determined by means of SPECT-CT - emission computed tomography with the following X-ray computed tomography. In case of impossibility to export volume zones of interest on the SPECT-CT images SLN topography is determined relative to adjoining anatomical structures and obtained information is transferred into the optic navigation system for identification and exact SLN detection in the process of performing the biopsy.

EFFECT: method makes it possible to identify true SLN, determine its exact topography and carry out its ablation by means of the optic navigation system, avoiding unjustified ablation of lymph nodes of the second and third order.

1 dwg, 1 ex