FIELD: medicine, pharmaceutics.
SUBSTANCE: there are presented a composition and a method for producing it. The characterised composition contains: an effective amount of a viral antigen, which represents a live attenuated rotavirus pre-processed in 0.1% human serum albumin, and a pharmaceutically acceptable buffer. A method for producing a composition involves growing Vero cell culture pre-cultured in the presence of 5% foetal calf serum and 0.1% human serum albumin, infecting the above Vero cell culture with the live attenuated rotavirus, propagating the virus in the cell culture and adding a pharmaceutically acceptable buffer to the above virus.
EFFECT: presented inventions can be used to prevent rotavirus infection and/or rotavirus gastroenteritis.
11 cl, 17 dwg, 4 tbl, 2 ex
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Authors
Dates
2015-06-10—Published
2010-01-25—Filed