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(19)

(11)

2 556 124

(13)

(51)

IPC

C12N1/20(2006-01-01)

A61K35/74(2015-01-01)

A61P37/00(2006-01-01)

A61P31/00(2006-01-01)

(21) (22)

Application

2011150202/10, 2010-05-07

(24)

Start date

2010-05-07

(22)

Actual filing date

2010-05-07

(45)

Published

2015-07-10

(72)

Inventor

Pti, ValeriGarsia-Rodenas, KlaraJulita, MonikPriu, GjunoleMersen'E, AnnikNjutten, Sofi

(73)

Holder

Nestek S.A.

Lactobacillus johnsonii La1 NCC533 (CNCM 1-1225) AND IMMUNE DISORDERS Russian patent published in 2015 - IPC C12N1/20 A61K35/74 A61P37/00 A61P31/00

Abstract RU 2556124 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates for composition for treatment or prevention of disorders, associated with reduced level of defensins. Composition contains from 0.005 to 1000 mg of Lactobacillus johnsonii Lal (NCC533, No CNCM 1-1225) per a daily dose, with at least 90% of L. johnsonii Lal (NCC533, No CNCM 1-1225) being transferred into state in which they become non-replicating at temperature110-140°C for 5-30 s.

EFFECT: invention provides enhancement of expression of defensin hBD1 mRNA.

5 cl, 2 dwg

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RU 2 556 124 C2

Authors

Pti, Valeri

Garsia-Rodenas, Klara

Julita, Monik

Priu, Gjunole

Mersen'E, Annik

Njutten, Sofi

Dates

2015-07-10—Published

2010-05-07—Filed