METHOD FOR PREDICTION OF HAEMATOGENIC METASTASIS IN DOUBLE-SIDED SYNCHRONOUS INVASIVE NON-SPECIFIC BREAST CARCINOMA Russian patent published in 2016 - IPC G01N33/48 

Abstract RU 2589287 C1

FIELD: medicine.

SUBSTANCE: invention is intended for predicting hematogenic metastasis in case of double-sided synchronous invasive carcinoma of non-specific mammary glands. Histological assessment of infiltrative component of neoplasms tissue in both mammary glands is carried out, during which the number of different structures from 1 to 5 is calculated, among which additionally alveolar, trabecular, solid structure and discrete groups of tumour cells are defined, presence of structures in points is estimated and Y regression equation value is calculated by formula: Y=(-41.1+2.2X1-1.3X2-0.74X3), then the value of haematogenous metastases development probability P is determined by formula: P=eY/(1+eY) and upon P≥50 % determine high, and upon P<50 % - low risk of haematogenous metastases development.

EFFECT: method increases accuracy and information value of hematogenic metastasis prediction.

1 cl, 2 ex, 2 tbl

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RU 2 589 287 C1

Authors

Zavyalova Marina Viktorovna

Fesik Evgeniya Anatolevna

Krakhmal Nadezhda Vasilevna

Vtorushin Sergej Vladimirovich

Slonimskaya Elena Mikhajlovna

Khristenko Kseniya Yurevna

Telegina Nadezhda Semenovna

Dates

2016-07-10Published

2015-02-03Filed