COMBINATION CRYOPROTECTOR "DIMETHYL SULPHOXIDE/RHEOPOLYGLUCIN" FOR STEM CELL CRYOPRESERVATION AND METHOD FOR CRYOPRESERVATION THEREOF FOR CLINICAL APPLICATIONS Russian patent published in 2015 - IPC A61K31/721 A61K35/12 A01N1/02 

Abstract RU 2563117 C1

FIELD: medicine.

SUBSTANCE: method for stem cell cryopreservation involves preparing a stem cell suspension and adding a cryoprotector solution to the above suspension with constant stirring, which is followed by cryopreservation, wherein the cyoprotector added to the suspension is 50% DMSO in rheopolyglucin to the final DMSO concentration of 10% in the prepared suspension. The group of inventions also concerns a combination cryoprotector for stem cell cryopreservation, containing 50% DMSO in rheopolyglucin.

EFFECT: creating the cryoprotector with a lower molecular weight and lower DMSO concentration for improving post-thawing cell preservation.

2 cl, 1 ex, 5 tbl

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RU 2 563 117 C1

Authors

Astrelina Tat'Jana Alekseevna

Kobzeva Irina Vladimirovna

Dates

2015-09-20Published

2014-12-24Filed