FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing ethyl 2-amino-2',5-dioxo-5'-phenyl-3-cyano-1',2'-dihydro-5H-spiro{indeno[1,2-b]pyran-4,3'-pyrrole}-4'-carboxylates of general formula , where R=CH2Ph, C6H11-c, H, Me, Et, carried out by reacting 5-phenyl-4-ethoxycarbonyl-1H-pyrrole-2,3-diones with malononitrile and indan-1,3-dione in the presence of triethylamine.
EFFECT: obtaining novel compounds which can be used as initial products for synthesis of novel heterocyclic systems and in pharmacology as compounds having analgesic activity.
3 cl, 1 tbl, 3 ex
Title |
Year |
Author |
Number |
ETHYL-2-AMINO-7,7-DIMETHYL-2',5-DIOXO-5'-PHENYL-1',2',5,6,7,8-HEXAHYDROSPIRO[CHROMEN-4,3'-PYRROL]-4'-CARBOXYLATES AND METHOD FOR PRODUCING THEM |
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|
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|
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|
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