METHOD OF PRODUCING ETHYL 2-AMINO-2',5-DIOXO-5'-PHENYL-3-CYANO-1',2'-DIHYDRO-5H-SPIRO{INDENO[1,2-B]PYRAN-4,3'-PYRROLE}-4'-CARBOXYLATES Russian patent published in 2015 - IPC C07D491/107 

Abstract RU 2569898 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing ethyl 2-amino-2',5-dioxo-5'-phenyl-3-cyano-1',2'-dihydro-5H-spiro{indeno[1,2-b]pyran-4,3'-pyrrole}-4'-carboxylates of general formula , where R=CH2Ph, C6H11-c, H, Me, Et, carried out by reacting 5-phenyl-4-ethoxycarbonyl-1H-pyrrole-2,3-diones with malononitrile and indan-1,3-dione in the presence of triethylamine.

EFFECT: obtaining novel compounds which can be used as initial products for synthesis of novel heterocyclic systems and in pharmacology as compounds having analgesic activity.

3 cl, 1 tbl, 3 ex

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RU 2 569 898 C1

Authors

Maslivets Andrej Nikolaevich

Dmitriev Maksim Viktorovich

Silajchev Pavel Sergeevich

Makhmudov Ramiz Ragibovich

Dates

2015-12-10Published

2014-12-16Filed