ETHYL 1'-BENZYL-3,3-DIMETNYL-1,2'-DIOXO-5'-PHENYL-1'2,2',3,4,10-HEXAHYDRO-1H-SPIRO[ACRIDINE-9,3'-PYRROL]-4'-CARBOXYLATES AND SYNTHESIS METHOD THEREOF Russian patent published in 2010 - IPC C07D417/10 A61K31/473 A61P29/00 

Abstract RU 2387651 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry, and more specifically to novel ethyl 5-R1-7-R2-1'-benzyl-3,3-dimethyl-1,2' -dioxo-5'-phenyl- 1',2,2',3,4,10-hexahydro-1H-spiro[acridine-9,3'-pyrrol]-4'-carboxylates of formula , where R1=H, Me; R2=H, OMe; R3=H, Me, OMe, Br, and to a method for synthesis of the said compounds.

EFFECT: obtaining novel compounds which can be used as primary products for synthesis of novel heterocyclic systems and in pharmacology as compounds with analgesic activity.

5 cl, 1 tbl, 3 ex

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RU 2 387 651 C1

Authors

Maslivets Andrej Nikolaevich

Silajchev Pavel Sergeevich

Makhmudov Ramiz Ragipovich

Dmitriev Maksim Viktorovich

Fedorovtseva Anastasija Nikolaevna

Dates

2010-04-27Published

2008-12-18Filed