DIAGNOSTIC TECHNIQUE FOR PROSTATE CANCER Russian patent published in 2015 - IPC A61B6/03 A61K49/04 

FIELD: medicine.

SUBSTANCE: technique involves prostate tomography followed by intravenous administration of a water-soluble contrast agent, which is presented by 50 ml of an iodine-containing non-ionic substance at a rate of administration of 5-7 ml/s. The tomography is performed in the dynamic mode by multispiral X-ray computed tomography in the three-dimensional mode 15, 18, 21, 24, 27, 30, 40, 45, 60, 70, 80 seconds from the moment of the administration of the contrast agent, at a slice thickness of 0.5mm. The formed images are analysed by constructing time variation curves of densitometric density of each volume picture element of the prostate and external iliac artery (EIA). A maximum average densitometric density of the EIA is calculated. Further, by each curve for each moment of time, a difference of the densitometric density of the volume picture element at this and following moment of time is determined by each curve; a segment with the maximum difference of the densitometric density is detected, and its maximum difference is related to the length of this segment. The derived value is further related to the maximum average density of the EIA. The calculated values reflex a specific volumetric blood flow in the volume picture element. The volumetric blood flow values for all the volume picture elements are used to plot a prostate perfusion chart, wherein the segments of the high volumetric blood flow corresponds to the tumour.

EFFECT: accurate localisation of prostate cancer, including the patients who are unable to be examined by magnetic resonant tomography.

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