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(19)

(11)

2 573 909

(13)

(51)

IPC

C07K14/555(2006-01-01)

(21) (22)

Application

2012141653/10, 2011-03-02

(24)

Start date

2011-03-02

(22)

Actual filing date

2011-03-02

(45)

Published

2016-01-27

(72)

Inventor

Allen JeffreyFeng Ping-HuaPatkar AnantHaney Keith L.Chew LawrenceSengchanthalangsy Lei Lei Phokham

(73)

Holder

Pfenex Inc.

METHOD FOR OBTAINING SOLUBLE RECOMBINANT INTERFERON PROTEIN WITHOUT DENATURATION Russian patent published in 2016 - IPC C07K14/555

Abstract RU 2573909 C2

FIELD: chemistry.

SUBSTANCE: claimed invention relates to field of production of recombinant proteins in bacterial hosts. Invention additionally relates to extraction of soluble, active recombinant protein from insoluble fraction without application of denaturation and without necessity of refolding stage.

EFFECT: invention relates to industrial method for obtaining large amounts of soluble recombinant protein of type I interferon from bacterial host.

19 cl, 9 dwg, 14 tbl, 9 ex

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RU 2 573 909 C2

Authors

Allen Jeffrey

Feng Ping-Hua

Patkar Anant

Haney Keith L.

Chew Lawrence

Sengchanthalangsy Lei Lei Phokham

Dates

2016-01-27—Published

2011-03-02—Filed