FIELD: medicine.
SUBSTANCE: presented group of inventions refers to pharmacogenetics and personalized medicine. Disclosed is a method of analyzing polymorphic markers in genes VKORC1, CYP4F2, CYP2C9, CYP2C19, ABCB1, ITGB3 to determine individual sensitivity to anticoagulant drugs and a set of oligonucleotide probes used in this method.
EFFECT: proposed group of inventions enables analysis in a short time and with low material costs.
4 cl, 2 dwg, 2 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF DETERMINING POLYMORPHIC MARKERS IN CYP2C19 AND CYP2D6 GENES FOR DETERMINING INDIVIDUAL SENSITIVITY TO ANTIDEPRESSANTS | 2018 |
|
RU2716589C1 |
| METHOD FOR ANALYSIS OF GENETIC POLYMORPHYSM, DEFINING PREDISPOSITION TO TUMOR DISEASES AND INDIVIDUAL SENSITIVITY TO PHARMACEUTICAL AGENTS BY USING OLYGONUCLEOTIDE BIOLOGICAL MICROARRAY (BIOARRAY) | 2005 |
|
RU2303634C2 |
| METHOD FOR DETERMINING POLYMORPHIC MARKERS IN SLCO1B1, APOE AND ABCB1 GENES FOR DETERMINING INDIVIDUAL SENSITIVITY TO STATINS | 2018 |
|
RU2695783C1 |
| METHOD FOR IDENTIFICATION OF GENETIC POLYMORPHISMS AFFECTING METABOLISM OF ANTICANCER DRUGS USING BIOLOGICAL MICROCHIPS | 2018 |
|
RU2697096C1 |
| METHOD OF POLYMORPHIC MARKERS ANALYSIS IN THE GENES OF METABOLISM OF MEDICINAL PREPARATIONS AND THE GENES OF IMMUNE RESPONSE IN THE ACUTE LEUCOSISES THERAPY IN CHILDREN | 2016 |
|
RU2643333C1 |
| SET OF OLIGONUCLEOTIDE PRIMERS AND PROBES FOR GENETIC TYPING OF POLYMORPHOUS DNA LOCI ASSOCIATED WITH A RISK OF PROGRESSION OF SPORADIC FORM OF ALZHEIMER'S DISEASE IN RUSSIAN POPULATIONS | 2014 |
|
RU2600874C2 |
| BIOLOGICAL MICROCHIP WITH PRIMER SET FOR ANALYSIS OF POLYMORPHISM IN AB0, HLA-DQA1, AMEL, DARC, NAT2 GENES | 2014 |
|
RU2582216C2 |
| METHOD FOR ANALYSING GENETIC POLYMORPHISM FOR DETERMINING DISPOSITION TO SCHIZOPHRENIA AND ALCOHOLISM | 2012 |
|
RU2565036C2 |
| METHOD FOR DETERMINING GENETIC MARKERS FOR ASSESSING POLYGENIC RISK OF DEVELOPING HORMONE-POSITIVE SUBTYPE OF BREAST CANCER | 2020 |
|
RU2753002C1 |
| BIOCHIP FOR MUTATION DETECTION IN GALACTOSE-1-PHOSPHATE-URIDYL TRANSFERASE GENE CAUSING HEPATIC INVOLVEMENT IN NEWBORNS | 2009 |
|
RU2423521C1 |
