FIELD: processes.
SUBSTANCE: invention relates to a method for purifying micafungin. Method comprises applying micafungin feedstock on a substrate of hydrophobic adsorber resin, exposing related micafungin to aqueous solution of a dissolved pharmaceutically acceptable salt, elution of dissolved pharmaceutically acceptable salt of micafungin with a solution containing an organic solvent miscible with water, wherein feedstock or aqueous solution contain an organic solvent, miscible with water.
EFFECT: invention simplifies method while maintaining high degree of purification.
27 cl, 9 dwg, 9 ex
| Title | Year | Author | Number |
|---|---|---|---|
| HIGH PURITY CYCLOPEPTIDE COMPOUND AS WELL AS PREPARATION METHOD AND USE THEREOF | 2013 |
|
RU2603345C2 |
| METHOD OF PURIFYING CYCLOPOLYPEPTIDE COMPOUNDS OR SALTS THEREOF | 2011 |
|
RU2535489C1 |
| METHOD OF PURIFYING CYCLOPEPTIDE COMPOUNDS OR SALTS THEREOF | 2011 |
|
RU2538274C2 |
| HIGH-PURITY CYCLOPEPTIDE CRYSTAL AS WELL AS PREPARATION METHOD AND USE THEREOF | 2013 |
|
RU2607083C2 |
| METHOD FOR ANTIFUGAL AGENT PRODUCTION | 2012 |
|
RU2575237C2 |
| 2-(AZAINDOL-2-YL)BENZIMIDAZOLE DERIVATIVES AS PAD4 INHIBITORS | 2012 |
|
RU2611010C2 |
| LIPOPEPTIDE PURIFICATION METHOD | 2010 |
|
RU2526391C2 |
| CONJUGATES FOR INTEGRIN ANTAGONIST TARGETED DELIVERY TO CELLS, EXPRESSING LFA-1 | 2013 |
|
RU2624731C2 |
| PYRANONE DERIVATIVE, METHOD OF ITS PREPARING AND PHARMACEUTICAL COMPOSITION | 1994 |
|
RU2098422C1 |
| HYDRATE OF CYCLOPEPTIDE COMPOUND AS WELL AS PREPARATION METHOD AND USE THEREOF | 2013 |
|
RU2594732C2 |
