FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to compounds of general formula
,
where R1 represents CH3; R2 represents halogeno or CN; R3 represents H or CH3; R4 represents H or CH3; n represents 0, 1 or 2; and to their pharmaceutically acceptable salts. Also, the invention refers to a pharmaceutical composition and to application of the compounds of formula (I) in preparing a drug exhibiting antagonist activity in relation to CX3CR1 receptor.
EFFECT: provided the compounds of formula (I) as CX3CR1 receptor antagonists.
20 cl, 1 tbl, 3 dwg, 10 ex
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