FIELD: medicine.
SUBSTANCE: invention refers to medicine and is in biodegradable particles for use as material for embolisation of vessels. Particles are obtained by dissolving synthetic polymer poly basic carboxylic acid and condensation of water-soluble carbodiimide in aprotic organic solvent, addition of obtained solution in droplets to bad solvent for said aprotic polar solvent and by chemical linking reaction in obtained drops. Water content in particles makes 20-90 % in water-saturated state. Invention also relates to method of producing said particles and to material for embolisation vessels.
EFFECT: technical result consists in fact that they have improved flexibility, brought to smaller aggregation between particles and can be easily delivered to selected point in blood vessel, without causing clogging of catheter; besides, particles retain shape that allows efficiency cause embolisation.
10 cl, 1 tbl, 10 ex
| Title | Year | Author | Number |
|---|---|---|---|
| BIODEGRADABLE PARTICLE, SUBSTANCE FOR VASCULAR EMBOLISATION AND METHOD OF PRODUCING BIODEGRADABLE PARTICLES | 2012 |
|
RU2585104C2 |
| BIODEGRADABLE PARTICLES FOR MEDICAL TREATMENT AND VESSEL EMBOLISATION MATERIAL | 2011 |
|
RU2578467C2 |
| BIODEGRADABLE MATERIAL AND METHOD OF PRODUCING BIODEGRADABLE MATERIAL | 2013 |
|
RU2588222C2 |
| BIODEGRADABLE MATERIAL AND METHOD OF PRODUCING BIODEGRADABLE MATERIAL | 2013 |
|
RU2572849C1 |
| POLYMERIC MATERIAL OF MEDICAL PURPOSE FOR EMBOLIZATION | 2017 |
|
RU2669801C1 |
| BIODEGRADABLE, SEMI-CRYSTALLINE, PHASE SEPARATED, THERMOPLASTIC MULTI-BLOCK COPOLYMERS FOR CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | 2012 |
|
RU2662818C2 |
| BIODEGRADABLE ALIPHATIC-AROMATIC POLYETHERS | 2006 |
|
RU2415879C2 |
| BIODEGRADABLE FLEXOGRAPHIC INK AND PREPARATION METHOD THEREOF | 2003 |
|
RU2398806C2 |
| STERILISATION OF BIODEGRADABLE HYDROGELS | 2010 |
|
RU2558847C9 |
| POLYMERIC COMPOSITION AND PROCESS FOR PREPARATION THEREOF | 1993 |
|
RU2126427C1 |
