METHOD FOR PREDICTION OF INTENSITY OF PAIN SYNDROME IN PATIENTS WITH CHRONIC CALCULOUS CHOLECYSTITIS IN EARLY POSTOPERATIVE PERIOD Russian patent published in 2016 - IPC G01N33/53 C12Q1/68 

FIELD: medicine.

SUBSTANCE: invention relates to medical diagnostics and concerns prediction of intensity of pain syndrome in early postoperative period in patients with chronic calculous cholecystitis, Russian ethnicity, which are natives of Central black earth region of Russia. Method involves blood sampling and DNA recovery from peripheral venous blood. After DNA is recovered, analysis of polymorphisms of genes IL-1A -889T>C, IL-5 -703C>T and more evident pain in patients with chronic calculous cholecystitis in 18 and 22 hours of first day after cholecystectomy if observing genotypes -889TT and -889CT IL-1A.

EFFECT: intensive predicted pain sensations in 8 hours of second postoperative day if observing genotypes -703CT and -703TT IL-5.

1 cl, 5 dwg