OPHTHALMIC COMPOSITION, CONTAINING PHENYLEPHRINE Russian patent published in 2016 - IPC A61K31/137 A61P27/02 

Abstract RU 2600863 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine, namely to ophthalmology. Ophthalmic composition contains water, phenylephrine, highly flexible substance, osmotic substance and buffer substance. Highly flexible substance is represented by hydroxypropyl methylcellulose in concentration range of 0.1-3 %. Osmotic substance is selected from group, consisting of salt and sugar. PH of composition makes 4-5.5. Osmolarity of composition is within 300-400 mosm. Method of producing said composition is also provided, which involves addition of phenylephrine to water solution, containing hydroxypropyl methylcellulose, buffer substance and osmotic substance.

EFFECT: usage of group of inventions allows to increase stability of composition at extended storage life.

16 cl, 3 tbl, 3 ex

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RU 2 600 863 C2

Authors

Bala Khani

Khasidzha Rakhul

Chaukhan Satish Kumar

Bakhri Dipak

Dates

2016-10-27Published

2008-10-07Filed