FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, namely to ophthalmology. Ophthalmic composition contains water, phenylephrine, highly flexible substance, osmotic substance and buffer substance. Highly flexible substance is represented by hydroxypropyl methylcellulose in concentration range of 0.1-3 %. Osmotic substance is selected from group, consisting of salt and sugar. PH of composition makes 4-5.5. Osmolarity of composition is within 300-400 mosm. Method of producing said composition is also provided, which involves addition of phenylephrine to water solution, containing hydroxypropyl methylcellulose, buffer substance and osmotic substance.
EFFECT: usage of group of inventions allows to increase stability of composition at extended storage life.
16 cl, 3 tbl, 3 ex
Title | Year | Author | Number |
---|---|---|---|
ANTI-INFLAMMATORY AND MYDRIATIC INTRA-CHAMBER SOLUTIONS FOR INHIBITION OF POSTOPERATIVE INFLAMMATORY EYE CONDITIONS | 2015 |
|
RU2750296C2 |
STABLE AQUEOUS SOLUTION | 2014 |
|
RU2665639C2 |
PHARMACEUTICAL COMPOSITIONS OF ATROPINE | 2018 |
|
RU2745603C1 |
Pharmaceutical composition based on tramadol for ophthalmic use | 2016 |
|
RU2744570C2 |
AN AQUEOUS MEDICINAL COMPOSITION SHOWING CAPABILITY OF REVERSIBLE THERMOREGULATED GEL-FORMATION | 1993 |
|
RU2108112C1 |
METHODS AND COMPOSITIONS FOR TREATING PRESBYOPIA, MYDRIASIS AND OTHER OCULAR DISORDERS | 2019 |
|
RU2824137C2 |
COMPOSITIONS AND METHODS FOR NON-SURGICAL TREATMENT OF PTOSIS | 2012 |
|
RU2582392C2 |
COMBINED OPHTHALMIC AGENT | 2019 |
|
RU2733392C1 |
DISULFIRAM AND TAURINE-CONTAINING OPHTHALMOLOGICAL MEDICATION IN FORM OF EYE DROPS | 2012 |
|
RU2485939C1 |
ANESTHETIC COMPOSITION AND METHOD OF EYE ANESTHETIZATION | 2020 |
|
RU2812900C2 |
Authors
Dates
2016-10-27—Published
2008-10-07—Filed